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Genetically Modified Drugs And Components
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| Roslin's chicken eggs could help save lives | |
| Midlothinan scientists have hit the headlines again after developing chickens capable of laying potentially life-saving eggs. Researchers at Roslin Institute, which created the world famous Dolly the Sheep, have produced five generations of the genetically-modified birds. The birds' egg whites are packed with proteins needed to make large quantities of drugs, which could be used to treat multiple sclerosis and skin cancer. The work, being led by Roslin Institute's Dr Helen Sang, is a joint Avian Transgenic Technology venture with biotechnology firms Viragen, based at Midlothian's Pentlands Science Park, and Oxford BioMedica. Roslin Institute director Professor Harry Griffin explained that Dr Sang's research had efficiently created transgenic chickens and been able to add a human gene and protein so they would only appear in the egg white and nowhere else in the bird. "The aim of this project is to use chickens as an inexpensive way of producing expensive medical proteins. A chicken has been engineered to produce two special human proteins, B-1a interferon, which is already in use for the treatment of multiple sclerosis, and a second protein, a mini antibody, which is being developed as a potential treatment for human skin cancer," said the professor. "The idea is that we will be able, in the future, to have relatively small flocks producing these proteins but that may not necessarily be in Midlothian." Professor Griffin said it would be five or more years before treatments could be available from this new technology. He added that it could be developed to treat other diseases, which required large quantities of human protein. Source: Midlothian Today All rights reserved © 2007 Johnston Press Digital Publishing.(17/01/07) © Multiple Sclerosis Resource Centre
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